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N/A N=296 Single-blind Health Services Research

Daily Checklists and Outcome in the Intensive Care Unit

Critical Illness

Enrolled (actual)
296
Serious AEs
0.0%
Results posted
Dec 2012
Primary outcome: Primary: Empiric Antibiotic Duration — 3; 3 days — p=0.27

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Electronic checklist (Other); Verbal prompting (Other)
Age
Pediatric, Adult, Older Adult
Sex
All
Sponsor
Northwestern University
Primary completion
Apr 2012

Outcome Measures

OutcomeResultp-value
PRIMARY
Empiric Antibiotic Duration
3; 3 0.27
PRIMARY
Proportion of Empiric Antibiotics
0.83; 0.78 0.093
SECONDARY
Hospital Mortality
30; 30 0.17
SECONDARY
Length of Stay
2.8; 2.6 0.27
SECONDARY
Ventilator-free Days
20.3; 21.9 0.36
SECONDARY
Proportion of Successful Prompts
0.096; 0.436
SECONDARY
Proportion of Patients-days on Which Empirical Antibiotics Were Used
498; 702 0.002 sig
SECONDARY
Standardized Mortality Ratio
0.70; 0.64

Summary

Medical errors account for tens of thousands of deaths and tens of billions of dollars in healthcare costs in the United States every year. One field that has seen the strongest push toward quality improvement has been critical care medicine, likely because its particularly high degree of medical complexity makes it a practice area prone to high error rates with serious consequences. One of the most commonly used interventions used to help reduce errors in the intensive care unit (ICU) has been the implementation of checklists. The investigators propose a clinical trial in a University critical care setting to determine whether an electronic checklist versus verbal prompting to use a written checklist improves clinical practice and patient outcomes. The investigators also plan to compare these data with a time period prior to the study to determine if the electronic checklist or verbal prompting are better than usual care. The investigators hypothesize that both the electronic checklist and verbal prompting to use a written checklist will be better for clinical practice and patient outcomes than usual care, and that verbal prompting will lead to better outcomes compared to the electronic checklist.

Eligibility Criteria

Inclusion Criteria

  • Admission to a medical intensive care unit (MICU) team during the study timeframe

Exclusion Criteria

  • Transfer from MICU team to a separate ICU team within 12 hours of admission
  • Transfer to MICU team from a separate ICU team after more than 72 hours on the separate ICU team
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01396044). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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