N/A
N=296
Daily Checklists and Outcome in the Intensive Care Unit
Critical Illness
Bottom Line
View on ClinicalTrials.gov: NCT01396044 ↗Enrolled (actual)
296
Serious AEs
0.0%
Results posted
Dec 2012
Primary outcome: Primary: Empiric Antibiotic Duration — 3; 3 days — p=0.27
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Electronic checklist (Other); Verbal prompting (Other)
- Age
- Pediatric, Adult, Older Adult
- Sex
- All
- Sponsor
- Northwestern University
- Primary completion
- Apr 2012
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Empiric Antibiotic Duration |
3; 3 | 0.27 |
| PRIMARY Proportion of Empiric Antibiotics |
0.83; 0.78 | 0.093 |
| SECONDARY Hospital Mortality |
30; 30 | 0.17 |
| SECONDARY Length of Stay |
2.8; 2.6 | 0.27 |
| SECONDARY Ventilator-free Days |
20.3; 21.9 | 0.36 |
| SECONDARY Proportion of Successful Prompts |
0.096; 0.436 | — |
| SECONDARY Proportion of Patients-days on Which Empirical Antibiotics Were Used |
498; 702 | 0.002 sig |
| SECONDARY Standardized Mortality Ratio |
0.70; 0.64 | — |
Summary
Medical errors account for tens of thousands of deaths and tens of billions of dollars in healthcare costs in the United States every year. One field that has seen the strongest push toward quality improvement has been critical care medicine, likely because its particularly high degree of medical complexity makes it a practice area prone to high error rates with serious consequences. One of the most commonly used interventions used to help reduce errors in the intensive care unit (ICU) has been the implementation of checklists.
The investigators propose a clinical trial in a University critical care setting to determine whether an electronic checklist versus verbal prompting to use a written checklist improves clinical practice and patient outcomes. The investigators also plan to compare these data with a time period prior to the study to determine if the electronic checklist or verbal prompting are better than usual care. The investigators hypothesize that both the electronic checklist and verbal prompting to use a written checklist will be better for clinical practice and patient outcomes than usual care, and that verbal prompting will lead to better outcomes compared to the electronic checklist.
Eligibility Criteria
Inclusion Criteria
- Admission to a medical intensive care unit (MICU) team during the study timeframe
Exclusion Criteria
- Transfer from MICU team to a separate ICU team within 12 hours of admission
- Transfer to MICU team from a separate ICU team after more than 72 hours on the separate ICU team
Data sourced from ClinicalTrials.gov (NCT01396044). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.