N/A
N=19
The Metabolic Effects of Breaks in Sedentary Time
Feasibility · Insulin · Glucose · Lipids · Eating
Bottom Line
View on ClinicalTrials.gov: NCT01398059 ↗Enrolled (actual)
19
Serious AEs
0.0%
Results posted
Jul 2019
Primary outcome: Primary: Change in Insulin Net Incremental Area-Under-The-Curve (iAUC) — 80559.3; 78707.3; 64270.8 pmol/L/min
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Sedentary (Other); Sedentary With Breaks (Other); Sedentary With Breaks and Physical Activity (Other)
- Age
- Pediatric · 10+ yrs
- Sex
- All
- Sponsor
- Children's Hospital of Eastern Ontario
- Primary completion
- Aug 2012
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Insulin Net Incremental Area-Under-The-Curve (iAUC) |
80559.3; 78707.3; 64270.8 | — |
| SECONDARY Change in Triglyceride Net Incremental Area-Under-The-Curve (iAUC) |
99.8; 101.5; 65.2 | — |
| SECONDARY Change in HDL-Cholesterol (HDL-C) Net Incremental Area-Under-The-Curve (iAUC) |
-38.7; -32.2; -52.3 | — |
| SECONDARY Change in LDL-Cholesterol (LDL-C) Net Incremental Area-Under-The-Curve (iAUC) |
-62.9; -50.0; -76.5 | — |
| SECONDARY Change in Glucose Net Incremental Area-Under-The-Curve (iAUC) |
185.3; 163.2; 248.0 | — |
Summary
The purpose of this study is to determine whether acute bouts of sedentary behaviour (with or without breaks and/or structured physical activity) result in measurable changes in metabolic health in children and youth.
Eligibility Criteria
Inclusion Criteria
- Age 10-14
- Normal weight or obese
Exclusion Criteria
- Overweight
- Overt diabetes or heart disease (or taking medications to treat this conditions)
- Being unambulatory or otherwise unable to perform the study protocol
Data sourced from ClinicalTrials.gov (NCT01398059). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.