Phase 3
Completed N=60
A Human Trial to Evaluate the Efficacy and Safety of Aged Garlic Powder on Improvement of Blood Lipids in Subjects With Hyperlipidemia
Source: ClinicalTrials.gov NCT01402102 ↗Enrolled (actual)
60
Serious AEs
—
Results posted
Oct 2012
Primary outcomePrimary: Changes in LDL-cholesterol(Low Density Lipoprotein - Cholesterol) — 150.6; 150.1; 155.8; 156.3 mg/dl
Summary
We performed a double-blind parallel study in a group of mildly hypercholesterolemic subjects who were given aged garlic powder over a period of 12 weeks. We measured serum lipids, including total cholesterol, low-density-lipoprotein (LDL) and high-density-lipoprotein (HDL) cholesterol, and triglycerides, and monitored their blood pressure.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Changes in LDL-cholesterol(Low Density Lipoprotein - Cholesterol) |
150.6; 150.1; 155.8; 156.3 | — |
| SECONDARY Changes in HDL-Cholesterol(High Density Lipoprotein - Cholesterol) |
46.86; 50.81; 50.36; 50.48 | — |
| SECONDARY Changes in Triglycerides |
139.79; 124.11; 120.21; 128.11 | — |
| SECONDARY Changes in Total Cholesterol |
241.07; 228.93; 233.50; 227.33 | — |
| SECONDARY Changes in Apo-A1(Apolipoprotein A1) |
1.48; 1.43; 1.41; 1.39 | — |
| SECONDARY Changes in Apo-B(Apolipoprotein B) |
1.21; 1.03; 1.07; 1.01 | — |
| SECONDARY Changes in FFA(Free Fatty Acid) |
570.25; 554.04; 618.14; 523.93 | — |
Eligibility Criteria
Inclusion Criteria
- Mild hypercholesterolemic subjects aged from 20 to 80 years
- had no received lipid-lowering drugs for at least 3 months prior to the recruitment
Exclusion Criteria
- self-reported pregnancy,lactation
- prevalent heart disease, cancer,renal disorder, or diabetes mellitus, and use of lipid or antihypertensive medications
Data sourced from ClinicalTrials.gov (NCT01402102). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.