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N/A Completed N=34 Randomized Treatment

Effect of HPIPC for the Treatment of Ischemic Ulcers in Subjects With PAD

PVD · Arterial Ulcers
Source: ClinicalTrials.gov NCT01420289 ↗
Enrolled (actual)
34
Serious AEs
0.0%
Results posted
Feb 2012
Primary outcomePrimary: Mean Percent Reduction in Wound Surface Area — 72; 58 Percent reduction in wound surface area — p=0.086

Summary

To evaluate the effects of HPIPC for the treatment of symptoms of PAD

Outcome Measures

OutcomeResultp-value
PRIMARY
Mean Percent Reduction in Wound Surface Area
72; 58 0.086
SECONDARY
Percent Improvement in Peak Walking Time
96; 66 <0.05 sig
SECONDARY
Perceived Improvement in Physical Function After 16 Weeks
70; 53
SECONDARY
Wound Pain as Determined by a Visual Analog 10 Point Scale (VAS) for Pain.
80; 55

Eligibility Criteria

Inclusion Criteria

  • Intermittent claudication >6mo
  • Ischemic ulceration or ulcer of mixed (venous) etiology
  • ABI < 0.7
  • Ambulatory
  • Able to comply

Exclusion Criteria

  • Gangrene
  • M.I. within 6mo
  • Inability to walk
  • Wound infection
  • Systemic corticosteroids
  • HBO, Apligraf, Dermagraft within 6mo
  • Falsely elevated ankle to brachial index (ABI)
  • Inflammatory condition affecting healing
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01420289). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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