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N/A N=6 Diagnostic

Evaluate the Use of Optical Frequency Domain Imaging (OFDI) for Celiac Disease in Children, Adolescents and Young Adults

Celiac Disease

Enrolled (actual)
6
Serious AEs
0.0%
Results posted
Sep 2018
Primary outcome: Primary: Number of Subjects With Changes of Villous Architecture Undergoing OFDI Imaging — 6 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
MGH OFDI Imaging (Device)
Age
Pediatric, Adult, Older Adult · 7+ yrs
Sex
All
Sponsor
Massachusetts General Hospital
Primary completion
Feb 2010

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Subjects With Changes of Villous Architecture Undergoing OFDI Imaging
6

Summary

The goal of this research is to conduct a pilot clinical study to image Celiac disease characteristic mucosal lesions and compare Optical Frequency Domain Imaging (OFDI) images to histologic evaluation in children, adolescents and young adults with suspected Celiac disease.

Eligibility Criteria

Inclusion Criteria

  • Age 7 years and above undergoing upper endoscopy for evaluation of celiac disease
  • Clinical history, physical findings, family history, or serologic evaluation suggestive of celiac disease
  • Parents/guardian available to sign informed consent

Exclusion Criteria

  • Patients with a history of hemostasis disorders
  • Use of Nonsteroidal anti-inflammatory drugs(NSAIDS) within ten days preceding initiation of the study
  • Use of any oral anticoagulation medication within one month preceding initiation of the study
  • Any known blood coagulation disorder
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01439035). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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