N/A
Completed N=300
Reengineering Methadone Treatment Study of Patient-centered Methadone Treatment
Opiate Dependence
Source: ClinicalTrials.gov NCT01442493 ↗
Enrolled (actual)
300
Serious AEs
22.7%
Results posted
Sep 2017
Primary outcomePrimary: Number of Participants With Opiate Positive Urine Tests — 89; 90 Participants — p=0.92
Summary
The purpose of the study is to determine whether a change in the rules and staff roles in methadone treatment programs will result in greater lengths of stay in treatment and lower rates of heroin and cocaine use, crime and HIV-risk behavior as compared to methadone treatment as usual.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Participants With Opiate Positive Urine Tests |
89; 90 | 0.92 |
| SECONDARY Number of Participants With Cocaine Positive Urine Tests |
67; 85 | 0.06 |
| SECONDARY Drug Use HIV Risk Behavior |
0.72; 1.36 | 0.08 |
| SECONDARY Criminal Behavior |
2.99; 3.72 | 0.54 |
| SECONDARY Global Score on the World Health Organization Quality of Life Measure |
3.70; 3.47 | .04 sig |
| SECONDARY Number of Participants Meeting DSM-IV Opiate Dependence Criteria |
88; 103 | 0.11 |
| SECONDARY Number of Participants Meeting DSM-IV Cocaine Dependence Criteria |
41; 52 | 0.21 |
Eligibility Criteria
Inclusion Criteria
- opiate dependence
- newly admitted to methadone treatment
Exclusion Criteria
- pregnancy
Data sourced from ClinicalTrials.gov (NCT01442493). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.