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Phase 1 Completed N=118 Randomized Triple-blind Treatment

Tailored Intervention to Promote Positive Airway Pressure Adherence

Sleep Apnea, Obstructive · Patient Compliance
Source: ClinicalTrials.gov NCT01454830 ↗
Enrolled (actual)
118
Serious AEs
0.0%
Results posted
Nov 2016
Primary outcomePrimary: Nightly CPAP Use — 6.4; 5.8 hours/night — p=0.20

Summary

The purpose of this study is to examine the feasibility of a tailored (i.e., individualized) intervention to promote adherence to continuous positive airway pressure therapy (CPAP) in adults with newly-diagnosed, CPAP treated, obstructive sleep apnea.

Outcome Measures

OutcomeResultp-value
PRIMARY
Nightly CPAP Use
4.8; 4.7 0.89
SECONDARY
Proportion of Sleep Time on CPAP
64.58; 65.73 0.78
SECONDARY
Proportion of Participants Who Complete Protocol After Allocation
88.5; 86
SECONDARY
Proportion of Participants Who Withdrawal
6.56; 7.02
SECONDARY
Acceptability of Study Intervention and Comparative Group
100; 100

Eligibility Criteria

Inclusion Criteria

  • males and females >/= 18 years of age
  • newly diagnosed with apnea/hypopnea index >/= 10 events/hr
  • CPAP naive
  • able to read and speak English

Exclusion Criteria

  • previous diagnosis and/or treatment of OSA
  • major new psychiatric diagnosis within 6 months of study enrollment
  • require supplemental oxygen or bilevel positive airway pressure on CPAP titration polysomnogram
  • diagnosis of co-existent sleep disorder on polysomnogram, including periodic limb movements >/= 10 events/hr with arousal, central sleep apnea with >/= 5 central events/hr, insomnia, sleep hypoventilation syndrome, or narcolepsy
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01454830). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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