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Phase 3 N=48 Randomized Double-blind Treatment

The Nasal Changes Affected by Different Alar Base Suture Techniques After Maxillary LeFort I Osteotomy

Conditions in T74.31 or T76.31

Enrolled (actual)
48
Serious AEs
0.0%
Results posted
Sep 2014
Primary outcome: Primary: Soft and Hard Tissue Landmarks Movement — 0.95; -0.5; -0.95; -0.32 mm — p=0.098

Study Design & Population

Study type
Interventional
Phase
Phase 3
Interventions
conventional alar base cinch (Procedure); modified alar base cinch (Procedure)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Chang Gung Memorial Hospital
Primary completion
Dec 2013

Outcome Measures

OutcomeResultp-value
PRIMARY
Soft and Hard Tissue Landmarks Movement
0.95; -0.5; -0.95; -0.32; 0.50; -0.71 0.098
SECONDARY
14 Nasolabial Linear Parameters
0.04; -0.62; 0.78; -0.80; 0.38; -0.81 0.218
SECONDARY
1 Nasolabial Angular Parameters
3.25; 2.92 0.104

Summary

study hypothesis 1. The aim of this study: How can the investigators predict and control the nasal changes after maxillary LeFort I osteotomy with 2 different alar base suture techniques ? 2. Study hypothesis * Null hypothesis: Nasal changes were not affected by 2 different alar base suture techniques after maxillary LeFort I osteotomy * Alternative : Nasal changes were affected by 2 different alar base suture techniques after maxillary LeFort I osteotomy

Eligibility Criteria

Inclusion Criteria

  • Taiwanese patients who received LeFort I osteotomy at CGMH during 2011-2012
  • No previous craniofacial surgery
  • Patients agreed to attend this study and willing to sign the agreement
  • Patients who are elder than 18 years old and after growth completion

Exclusion Criteria

  • Craniofacial anomalies
  • cleft lip and /or palate patients
  • patients without all the documents
  • patients do not receive combined correcting nasolabial shape and orthognathic surgery.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01473745). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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