N/A Completed N=38 Randomized Treatment

Fluoride Varnish for Treatment of White Spot Lesions

White Spot Lesions

Source: ClinicalTrials.gov NCT01500187 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Feb 2019

Primary outcomePrimary: DIAGNOdent Readings at Baseline, Three and Six Months - Intergroup Comparison — 5.10; 6.01; 4.08; 5.50 units on a scale — p=0.636

Summary

Study will look at ability of fluoride varnish to remineralize white spot enamel lesions that can occur around the edge of fixed orthodontic brackets.

Outcome Measures

Outcome	Result	p-value
PRIMARY DIAGNOdent Readings at Baseline, Three and Six Months - Intergroup Comparison	5.10; 6.01; 4.08; 5.50; 3.52; 3.95	0.636

Eligibility Criteria

Inclusion Criteria

no systemic disease
has completed fixed orthodontic treatment, brackets debonded
has at least two teeth with whitre spot lesions
has received conventional periodontal therapy after orthodontic tretament

Exclusion Criteria

presence of enamel hypoplasia or dental fluorosis
presence of tetracycline pigmentation
periodontal pocketing of 3mm or greater
taking antibiotics
presence of carious cavities
allergy to fluoride gel / varnish being used in study

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01500187). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.