Phase 4 N=12 Randomized Double-blind Other

Determination of the Duration of Action of a Lidocaine and a Bupivacaine Digital Nerve Block in Human Volunteers

Onset and Duration of a Digital Nerve Block

Bottom Line

View on ClinicalTrials.gov: NCT01508832 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Aug 2013

Primary outcome: Primary: The Change in the Average Finger Temperature From Baseline to Post-intervention. — -1.35; 0.93 degrees centigrade

Study Design & Population

Study type: Interventional
Phase: Phase 4
Interventions: Lidocaine Digital Nerve Block (Drug); Bupivacaine Digital Block (Drug)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: University of California, San Francisco
Primary completion: Mar 2013

Outcome Measures

Outcome	Result	p-value
PRIMARY The Change in the Average Finger Temperature From Baseline to Post-intervention.	-1.35; 0.93	—

Summary

The duration of the autonomic (sympathetic) block will last longer than the sensory block. The duration of the increased perfusion index will last longer than either the sympathetic or sensory block.

Eligibility Criteria

Inclusion Criteria

Non-smokers

Exclusion Criteria

History of allergic response to local anesthetics
BMI >25
Pregnant of nursing
Current smokers or past smokers of > 1 pack year history
Neurological deficit and/or injury in the upper extremities
Current respiratory infection
Per investigator judgement, would not be suitable for study

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Data sourced from ClinicalTrials.gov (NCT01508832). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.