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N/A N=32 Randomized Double-blind

Effects of Light Emitting Diode Irradiation on the Conduction Parameters of the Superficial Radial Nerve

Peripheral Neuropathy

Enrolled (actual)
32
Serious AEs
0.0%
Results posted
Jul 2013
Primary outcome: Primary: Nerve Conduction Velocity (Meters Per Second) — 0.000; -0.358; 0.447; 0.147 m/s

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Superluminous light diode (Device)
Age
Adult · 18+ yrs
Sex
All
Sponsor
Shenandoah University
Primary completion
Sep 2008

Outcome Measures

OutcomeResultp-value
PRIMARY
Nerve Conduction Velocity (Meters Per Second)
0.000; -0.358; 0.447; 0.147; -0.041; 0.280
SECONDARY
Negative Peak Latency (Milliseconds)
0.000; 0.414; 0.007; -0.007; 0; -0.014
SECONDARY
Temperature (Degrees C)
0.000; 0.414; 0.993; 0.686; 0.757; 0.786

Summary

The introduction of light emitting diode (LED) devices as a novel treatment for pain relief in place of low-level laser warrants fundamental research on the effect of LED devices on one of the potential explanatory mechanisms: peripheral neurophysiology in vivo. A randomized controlled study will be conducted by measuring nerve conduction on the superficial radial nerve of healthy subjects (n=64). One baseline measurement and five post-irradiation recordings (2-min interval each) will be performed of the nerve conduction velocity (NCV) and peak latency (PL) and peak amplitude (PA). The experimental group (=32) will receive an irradiation of 2 J/cm2 with an infrared LED device (Dynatronics Solaris Model 705), while the placebo group will be treated by sham irradiation. The purpose of this study is to investigate the effects of LED light on the conduction velocity and amplitude of the superficial radial nerve.

Eligibility Criteria

Inclusion Criteria

  • no history of neurological disease, polyneuropathy, peripheral neuropathy or cervical radiculopathy

Exclusion Criteria

  • positive findings during the clinical screening examination suggestive of an underlying neurological disease, polyneuropathy, peripheral neuropathy or cervical radiculopathy.
  • a history of a neurological disease, polyneuropathy, peripheral neuropathy or cervical radiculopathy.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01513148). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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