N/A
Completed N=252
Antimicrobial Stewardship Through MRSA Diagnosis in Emergency Department (ED) Patients With Abscesses
Cutaneous Abscess
Source: ClinicalTrials.gov NCT01523899 ↗
Enrolled (actual)
252
Serious AEs
—
Results posted
Sep 2017
Primary outcomePrimary: Number of Participants With Antibiotic Usage at the Time of the ED Visit — 97; 96 Participants
Summary
This study expands upon pilot data for feasibility since May 2011. The study aims to evaluate the effect of rapid test availability on use of targeted spectrum antibiotics for non-MRSA abscesses in ambulatory patients in the Emergency Department (ED). The multi-institutional study will assess the feasibility of providing the GeneXpert® MRSA/SA SSTI assay to the ED and evaluate the impact of delivering the test result to clinicians in real-time on patient management decisions regarding the use of antimicrobial agents. Patients are randomized to standard culture (control arm) or to the GeneXpert® assay plus standard culture.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Participants With Antibiotic Usage at the Time of the ED Visit |
97; 96 | — |
| SECONDARY Participant Clinical Improvement Post-treatment at One Week |
91; 94 | >0.05 |
| SECONDARY Clinical Outcome at One or Three Months |
26; 24 | — |
Eligibility Criteria
Inclusion Criteria
- adults 18 years or older with community onset abscess
Exclusion Criteria
- previous treatment for same abscess in past 14 days
- postoperative infection
- inability to provide informed consent
Data sourced from ClinicalTrials.gov (NCT01523899). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.