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N/A N=33

Taste Perception Pre and Post Bariatric Surgery

Morbid Obesity

Enrolled (actual)
33
Serious AEs
0.0%
Results posted
Jul 2014
Primary outcome: Primary: Changes on Taste Detection Thresholds After Bariatric Surgery-induced Weight Loss (Roux-en-Y Gastric Bypass and Laparoscopic Adjustable Banding). — 7.5; 8.1; 6.5; 7.5 mmol/L — p=0.19

Study Design & Population

Study type
Observational
Phase
N/A
Interventions
Gastric bypass (Procedure); Gastric banding (Procedure); Sleeve gastrectomy (Procedure)
Age
Adult, Older Adult · 20+ yrs
Sex
All
Sponsor
Washington University School of Medicine
Primary completion
May 2013

Outcome Measures

OutcomeResultp-value
PRIMARY
Changes on Taste Detection Thresholds After Bariatric Surgery-induced Weight Loss (Roux-en-Y Gastric Bypass and Laparoscopic Adjustable Banding).
7.5; 8.1; 6.5; 7.5 0.19
SECONDARY
Changes on Emotional, External and Restricted Eating Behavior and Food Craving After Bariatric Surgery-induced Weight Loss (Roux-en-Y Gastric Bypass and Laparoscopic Adjustable Gastric Banding).
2.3; 2.7; 1.6; 2.3; 2.9; 2.6

Summary

The investigators wish to study the effects of three forms of bariatric surgery, gastric bypass lap banding, and sleeve gastrectomy. The surgery is not part of the clinical trial. If your insurance does not cover the procedure, then the patient is responsible for payment of the surgical process. The investigators are doing pre and post surgery testing to provide a better understanding of the effect of bariatric surgery-induced weight-loss on taste perception.

Eligibility Criteria

Inclusion Criteria

  • BMI >=35 kg/m²
  • on stable dose of medication for at least 4 weeks before the pre-surgery studies
  • women

Exclusion Criteria

  • smokes > 7 cigarettes per day
  • previous malabsorptive or restrictive intestinal surgery
  • pregnant or breastfeeding
  • recent history of neoplasia (< 5 years ago)
  • have malabsorptive syndromes and inflammatory intestinal disease
  • diabetes mellitus
  • show signs of oral disease or xerostomia (i.e. dry mouth)
  • history of chronic rhinitis
  • on medication that might affect taste
  • severe organ disfunction
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01536197). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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