N/A
Completed N=36
EEG Studies of Induction and Recovery From Propofol Induced General Anesthesia
Brain Activity Under Sedation
Source: ClinicalTrials.gov NCT01543633 ↗
Enrolled (actual)
36
Serious AEs
0.0%
Results posted
Jan 2022
Primary outcomePrimary: EEG Power in Alpha, Slow, and Delta Bands — 10; 0.55; 2.5 Power of alpha band (decibels)
Summary
The purpose of this study is to investigate how the commonly used anesthetic drug propofol works in the brain to produce loss of consciousness. While under general anesthesia your brain waves will be measured using electroencephalogram (EEG). On a separate day, the patient's brain will be imaged using magnetic resonance imaging (MRI).
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY EEG Power in Alpha, Slow, and Delta Bands |
10; 0.55; 2.5 | — |
Eligibility Criteria
Inclusion Criteria
- Healthy, non-smoking male and female volunteers, ages 18-36 with normal body weight.
- American Society of Anesthesiologists (ASA) physical status I
Exclusion Criteria
- History of head trauma
- Surgical aneurysm clips
- Cardiac pacemaker
- Prosthetic heart valve
- Neurostimulator
- Implanted pumps
- Cochlear implants
- Metal rods, plates
- Screws
- Intrauterine device
- Hearing aid
- Dentures (which might create NMR artifacts)
- Metal injury to eyes
Data sourced from ClinicalTrials.gov (NCT01543633). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.