N/A
N=105
Primary Cell Culture of Hepatic Tumorous Cells From Routine Fine-needle Aspiration
Hepatocellular Carcinoma
Bottom Line
View on ClinicalTrials.gov: NCT01549275 ↗Enrolled (actual)
105
Serious AEs
—
Results posted
Oct 2015
Primary outcome: Primary: Correlation Between the Growth Speeds of the Cultured Cells and the AJCC TNM Stage (7th Eds) at Entering of the Study. — 21; 29; 14; 9 participants — p=< 0.005
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- —
- Age
- Adult, Older Adult · 20+ yrs
- Sex
- All
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
- Primary completion
- Jan 2013
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Correlation Between the Growth Speeds of the Cultured Cells and the AJCC TNM Stage (7th Eds) at Entering of the Study. |
21; 29; 14; 9; 7; 20 | < 0.005 sig |
| SECONDARY Correlation Between the Growth Speeds of Cultured Cells and Worsening of AJCC TNM Stages or HCC Related Death 6 Months After Plating of Cells |
10; 15; 3; 9; 12; 0 | 1 |
Summary
The purposes of this prospective study were to evaluate the successful rate of primary culture of hepatocellular carcinoma cells and cancer-associated fibroblasts from the residual specimens in routine fine-needle aspiration of hepatic tumor and the potential application of this method as an additional tool for personalized treatment of hepatocellular carcinoma patients.
Eligibility Criteria
Inclusion Criteria
- patients had residual aspirated specimens for primary culture.
Exclusion Criteria
- patients did not have residual aspirated specimens for primary culture.
Data sourced from ClinicalTrials.gov (NCT01549275). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.