N/A
N=149
Hub Cleansing to Prevent Hub Infection
Bacteremia
Bottom Line
View on ClinicalTrials.gov: NCT01563406 ↗Enrolled (actual)
149
Serious AEs
0.0%
Results posted
Apr 2016
Primary outcome: Primary: Number of Central Venous Catheter Hubs With Internal Contamination — 42; 18; 39; 14 contaminated hubs
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- 15 second scrub (Other); 5 second scrub (Other); 3.15% chlorhexidine/70% isopropyl alcohol (Drug); 70% isopropyl alcohol (Drug)
- Age
- Pediatric, Adult, Older Adult · 16+ yrs
- Sex
- All
- Sponsor
- Rush University Medical Center
- Primary completion
- Jun 2013
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Central Venous Catheter Hubs With Internal Contamination |
42; 18; 39; 14 | — |
| SECONDARY Number of Contaminated Central Venous Catheter Tips |
— | — |
| SECONDARY Median Number of Microbial Colony Forming Units Per Hub Interior |
0; 0; 0; 0 | — |
Summary
Central venous catheter infections are common preventable adverse events among hospital patients. Microbes may enter catheter hubs, also known as needleless connectors, and result in downstream contamination. This study aims to compare alcohol disinfection of catheter hubs to disinfection with chlorhexidine gluconate in alcohol, which has been proven to be a superior disinfectant at the site of central venous catheter insertion. Scrub duration of central venous catheter hubs will also be evaluated.
Eligibility Criteria
Inclusion Criteria
- Medical intensive care unit patients with non-tunneled central venous catheters
Exclusion Criteria
- Dialysis catheters
- Antibiotic-impregnated catheters
- Introducer sheaths
- Tunneled catheters
Data sourced from ClinicalTrials.gov (NCT01563406). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.