N/A N=50

HRQoL in the Low MELD Pre-tx Population

Cirrhosis of the Liver

Bottom Line

View on ClinicalTrials.gov: NCT01573325 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Feb 2014

Primary outcome: Primary: Perceived HRQoL Score. Overall Qualty of Life Index Tool Was Utilized. — 20.19 scores on a scale

Study Design & Population

Study type: Observational
Phase: N/A
Interventions: —
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Northwestern University
Primary completion: Jul 2012

Outcome Measures

Outcome	Result	p-value
PRIMARY Perceived HRQoL Score. Overall Qualty of Life Index Tool Was Utilized.	20.19	—
SECONDARY Percentage of Subjects With Depressive Scores Who Had a Poor HRQoL	78	—

Summary

The purpose of this study is to describe the HRQoL in those with MELD scores </= 15 in a single center for those who are pre-liver transplant candidates

Eligibility Criteria

Inclusion Criteria

Must be a patient in the liver transplant clinic at Northwestern Memorial Hospital or one of its satellite clinics (including Washington, Illinois; Portage, Indiana; Glenview, Illinois, Oakbrook, Illinois; Joliet, Illinois)
Adult patient between the ages of 18-75
Ability to read and speak English
Must be a candidate for liver transplant per Northwestern Memorial Hospital liver transplant multidisciplinary committee
Model for End Stage Liver Disease (MELD) score ≤15
Cognitive ability to complete measures

Exclusion Criteria

Non-English speaking
Those who have already received a liver transplant
Hepatic encephalopathy as evidenced by:
Grade II or more West Haven Criteria or Adapted West Haven Criteria
Evidence of Asterixis upon exam at time of consent (if consented in person)
Acute liver failure as etiology for liver disease.
MELD score > 15
Mental retardation or cognitive disabilities preventing completion of the written questionnaire

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01573325). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.