Phase 3
Completed N=15
Enhancing Hair Density With Platelet Rich Fibrin Matrix (PRFM)
Alopecia
Source: ClinicalTrials.gov NCT01590238 ↗
Enrolled (actual)
15
Serious AEs
0.0%
Results posted
Nov 2016
Primary outcomePrimary: Hair Density Change After Three Treatments — 175.1 percentage of pre-treatment hair density
◆ Published Evidence
No publication linked
No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.
Summary
Clinical alopecia occurs due to miniaturization of the hair shafts as well as loss of active production of hair shafts. PRFM has been shown to induce dermal angiogenesis, and anecdotal findings of improvement of hair appearance after PRFM injection in the scalp suggest that PRFM may play a role in the treatment of thinning hair. Patients will be treated on a monthly basis with intradermal injections of autologous PRFM for 3 months. Changes in hair density will be assessed by comparing pre- and post-treatment photographs and non-invasive measurements of hair density at 1, 2, 3, 4 and 6 months after initial treatment.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Hair Density Change After Three Treatments |
175.1 | — |
Eligibility Criteria
Inclusion Criteria
- age 18- 75 years old
- frontal and/or crown alopecia
Exclusion Criteria
- bleeding disorder
Data sourced from ClinicalTrials.gov (NCT01590238). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.