Phase 1
Completed N=33
Ability of Partial Inverse Agonist, Iomazenil, to Block Ethanol Effects in Humans
Active Ethanol and Active Iomazenil · Active Ethanol and Placebo Iomazenil · Placebo Ethanol and Active Iomazenil · Placebo Ethanol and Placebo Iomazenil
Source: ClinicalTrials.gov NCT01590277 ↗
Enrolled (actual)
33
Serious AEs
0.0%
Results posted
Oct 2024
Primary outcomePrimary: Biphasic Ethanol Effects Scale (BAES) — 3.767; 3.935; 3.813; 3.194 score on a scale
Summary
Alcohol is abused commonly, but there is no remedy for alcohol intoxication. This project is looking at the substance iomazenil and its effect on alcohol intoxication and alcohol's effects on driving using a driving simulator.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Biphasic Ethanol Effects Scale (BAES) |
3.767; 3.935; 3.813; 3.194; 4.767; 4.484 | — |
Eligibility Criteria
Inclusion Criteria
- Males
- 21-35 years old
- Medically healthy
Exclusion Criteria
- Under the age of 21 or greater than the age 35
- History of seizures
Data sourced from ClinicalTrials.gov (NCT01590277). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.