Phase 3
Completed N=113
Clinical Efficacy of a Toothpaste in Providing Relief From the Pain of Dentinal Hypersensitivity
Dentine Hypersensitivity
Source: ClinicalTrials.gov NCT01592851 ↗
Enrolled (actual)
113
Serious AEs
0.0%
Results posted
Jun 2014
Primary outcomePrimary: Change From Baseline in Evaporative Air Sensitivity Pain Response on a Schiff Sensitivity Scale at Day 14 — -1.20; -0.37 Score on a scale — p=<0.0001
Summary
A study to compare the efficacy of a test dentifrice against a control dentifrice in reducing dentinal hypersensitivity over a two week treatment period.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change From Baseline in Evaporative Air Sensitivity Pain Response on a Schiff Sensitivity Scale at Day 14 |
-1.20; -0.37 | <0.0001 sig |
| SECONDARY Change From Baseline in Evaporative Air Sensitivity Pain Response on a Schiff Sensitivity Scale Immediately Post-treatment |
-0.40; -0.14 | 0.0006 sig |
| SECONDARY Change From Baseline in Evaporative Air Sensitivity Pain Response on a Schiff Sensitivity Scale at Day 3 |
-0.70; -0.25 | <0.0001 sig |
| SECONDARY Change From Baseline in Tactile Pain Threshold Score at Day 14 |
22.9; 3.5 | <0.0001 sig |
| SECONDARY Change From Baseline in Tactile Pain Threshold Score at Day 3 |
9.8; 3.0 | 0.0021 sig |
| SECONDARY Change From Baseline in Tactile Pain Threshold Score Immediately Post-treatment |
5.8; 1.9 | 0.0070 sig |
Eligibility Criteria
- Subjects who suffer from tooth sensitivity.
Data sourced from ClinicalTrials.gov (NCT01592851). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.