Phase 3
Completed N=118
The Efficacy of a Dentifrice in Providing Relief From the Pain of Dentinal Hypersensitivity
Dentine Hypersensitivity
Source: ClinicalTrials.gov NCT01592864 ↗
Enrolled (actual)
118
Serious AEs
0.9%
Results posted
Mar 2014
Primary outcomePrimary: Mean Change From Baseline in Evaporative Air Sensitivity Pain Response on a Schiff Sensitivity Scale at Week 8 — -0.9; -0.5 Score on a scale — p=<0.0001
Summary
A study to compare the efficacy of a test dentifrice against a control dentifrice in reducing dentinal hypersensitivity over an eight week treatment period.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Mean Change From Baseline in Evaporative Air Sensitivity Pain Response on a Schiff Sensitivity Scale at Week 8 |
-0.9; -0.5 | <0.0001 sig |
| SECONDARY Mean Change From Baseline in Evaporative Air Sensitivity Pain Response on a Schiff Sensitivity Scale at Week 4 |
-0.7; -0.2 | <0.0001 sig |
| SECONDARY Adjusted Mean Change From Baseline in Tactile Sensitivity Pain Response at Week 8 |
21.3; 4.2 | <0.0001 sig |
| SECONDARY Adjusted Mean Change From Baseline in Tactile Sensitivity Pain Response at Week 4 |
11.2; 1.5 | <0.0001 sig |
Eligibility Criteria
Inclusion Criteria
- Subjects who suffer from tooth sensitivity
Inclusion Criteria
- none
Data sourced from ClinicalTrials.gov (NCT01592864). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.