N/A
Completed N=55
Exercise Therapy Program in Ankylosing Spondylitis Patients
Source: ClinicalTrials.gov NCT01690273 ↗Enrolled (actual)
55
Serious AEs
0.0%
Results posted
Oct 2016
Primary outcomePrimary: FUNCTIONAL INDEX — 3.4; 4.3; 3.2; 4.5 units on a scale — p=0.13
Summary
Mobility exercises are used in Ankylosing Spondylitis (AS) patients to preserve and restore axial mobility, but there are no data regarding a specific rehabilitation program that includes flexibility alone and its association with resistance exercises in AS patients with stable disease activity. So, we assessed the effects of two exercise programs in terms of mobility, functional capacity, quality of life and disease activity in AS patients. Methods. Fifty-five sedentary AS patients with a Bath Ankylosing Spondylitis Activity Index (BASDAI) <4 were included.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY FUNCTIONAL INDEX |
3.4; 4.3; 3.2; 4.5; 4.0; 2.2 | 0.13 |
| PRIMARY Mobility Index |
4.3; 5.3; 4.5; 4.6; 4.8; 4.0 | 0.04 sig |
| PRIMARY Disease Activity Index |
2; 2.6; 2.1; 3.2; 2.9; 1.7 | 0.004 sig |
| PRIMARY Ankylosing Spondylitis Disease Activity Scale -Disease Activity |
1.8; 1.7; 1.5; 2.2; 1.6; 1.4 | 0.09 |
| PRIMARY Global Evaluation Self Reported |
3.6; 5.0; 4.1; 5.6; 4.7; 3.4 | 0.003 sig |
| SECONDARY Thoracolumbar Mobility |
1.9; 1.4; 1.6; 1.7; 2.1; 2.6 | 0.853 |
| SECONDARY Pain Scale |
1.8; 2.5; 2.0; 2.3; 2.4; 2.0 | 0.07 |
| SECONDARY Stiffness Scale |
3.1; 3.1; 3.1; 4.3; 4.2; 2.8 | 0.88 |
| SECONDARY Short Form-12 (PCS) |
42.3; 38.8; 43.9; 41.9; 40.9; 44.8 | 0.9 |
| SECONDARY Short Form-12 (MCS) |
51.8; 45.7; 47.1; 52.1; 46.0; 51.6 | 1 |
| SECONDARY MASES |
0.7; 1.5; 0.8; 1.3; 1.1; 0.7 | 0.8 |
| SECONDARY Chin-coronoid Distance |
9.9; 14.2; 10.9; 10.0; 9.5; 9.2 | 1 |
| SECONDARY Tragus-coronoid Distance |
9.9; 12.3; 9.7; 10.1; 9.0; 8.8 | 0.997 |
| SECONDARY Finger Floor Distance |
27.6; 27.1; 23.7; 29.5; 24.2; 20.3 | 0.787 |
| SECONDARY Chest Expansion |
2.8; 2.8; 3.6; 3.0; 3.3; 4.3 | 0.978 |
Eligibility Criteria
Inclusion Criteria
- Ankylosing spondylitis patient
- Basdai index lower than 4
- Physical inactive
- Functional class I to III
Exclusion Criteria
- Fibromyalgia
- Cardiovascular disease
- Pain Visual Analogue Scale ("VAS") over 8
Data sourced from ClinicalTrials.gov (NCT01690273). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.