Phase 3
Completed N=48
Effectiveness of Mirror Therapy in Stroke Patients With Unilateral Neglect - A Randomized Controlled Trial
Hemispatial Neglect
Source: ClinicalTrials.gov NCT01735877 ↗
Enrolled (actual)
48
Serious AEs
0.0%
Results posted
Jun 2014
Primary outcomePrimary: Change From Baseline in Star Cancellation Test Scores at 1,3, and 6 Months — 17.88; 18.20; 20.03; 5.90 units on a scale — p=0.77
Summary
Hemi spatial neglect, or the tendency to ignore stimuli originating in a portion of the environment contra lateral to a cerebral lesion, can be a major source of functional handicap after stroke. The currently available treatments for unilateral neglect are scanning training, visual cuing approaches, limb activation strategies, visual imagery, tactile stimulation, prisms and sustained attention training.Mirror therapy improves the hand function in sub-acute stroke.
Hypothesis: To evaluate the effectiveness of Mirror therapy in the management of stroke patients with unilateral neglect.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change From Baseline in Star Cancellation Test Scores at 1,3, and 6 Months |
17.88; 18.20; 20.03; 5.90; 31.76; 9.2 | 0.77 |
| PRIMARY Change From Baseline in Line Bisection Test Scores at 1,3, and 6 Months |
2.28; 0.45; 10.42; 4.50; 18.26; 9.55 | 0.64 |
| PRIMARY Change From Baseline in Picture Identification Task at 1,3, and 6 Months |
4.84; 4.20; 4.88; 1.2; 5.16; 1.75 | 0.99 |
| SECONDARY Functional Independence Measure |
27; 21; 26; 20; 18; 19 | 0.99 |
| SECONDARY Modified Rankin Scale (mRS) |
27; 21; 25; 20; 16; 19 | 0.99 |
Eligibility Criteria
Inclusion Criteria: 1.All stroke patients with parietal lobe and thalamic lesions 2. Stroke duration: within 48 hours 3. Patients willing to participate in the study 4. MRI/ CT scan showing parietal lobe and thalamic lesion 5. Patients with upper limb weakness
Exclusion Criteria
- Stroke duration more than 1 yr
- Glasgow Coma Scale (GCS) of less than 7
- Uncooperative patients
Data sourced from ClinicalTrials.gov (NCT01735877). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.