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N/A N=416 Randomized Treatment

Improving Decision Making for Patients With Prolonged Mechanical Ventilation

Surrogate Decision Makers · Prolonged Mechanical Ventilation

Enrolled (actual)
416
Serious AEs
0.0%
Results posted
May 2019
Primary outcome: Primary: Change in Clinician-surrogate Concordance Scale Score — -6.6; -4.8; 33.6; 34.3 score on a scale — p=<0.05

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Decision aid (Behavioral); Usual care (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Duke University
Primary completion
May 2016

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in Clinician-surrogate Concordance Scale Score
-6.6; -4.8; 33.6; 34.3; 27.1; 29.5 <0.05 sig
SECONDARY
Hospital Anxiety and Depression Scale (HADS) Total Score
-3.8; -4.0 <0.05 sig
SECONDARY
Post-traumatic Stress Syndrome Inventory
-1.7; -1.4 <0.05 sig
SECONDARY
Patient-centeredness of Care Scale
42.7; 41.8 <0.05 sig
SECONDARY
Medical Comprehension Scale Score
0.8; 0.5 <0.05 sig
SECONDARY
Quality of Communication Scale Score
4; 7.0 <0.05 sig
SECONDARY
Change in Clinical-surrogate Concordance Scale Score (Nurse)
-5.4; -6.2 <0.05 sig

Summary

Deciding about prolonged life support for critically ill patients can be very difficult. Therefore, the investigators are doing a study to see if an internet-based decision aid can improve the quality of decision making for substitute decision makers of patients who are in the intensive care unit (ICU).

Eligibility Criteria

Inclusion Criteria (Patient characteristics required for surrogate inclusion)

  • age ≥18
  • ≥10 days of mechanical ventilation interrupted by 21 days.

Inclusion criteria for surrogate decision makers:

  • age ≥18
  • self-identified as participating directly in health care decision making for the incapable patient under relevant state law

Exclusion criteria for surrogate decision makers:

  • do not personally know the patient
  • need translation assistance because of poor English fluency (the decision aid has not been validated in other languages)
  • history of clinically important neurological disorder (e.g., dementia)
  • patient dies after meeting inclusion criteria but before surrogates provide consent

Physician and nurse inclusion criteria:

  • ICU attending or fellow (physicians) at the time of surrogate enrollment
  • bedside ICU nurse present at the time of surrogate enrollment
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01751061). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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