N/A
Completed N=351
Allergens in Inner-City Schools and Childhood Asthma
Source: ClinicalTrials.gov NCT01756391 ↗Enrolled (actual)
351
Serious AEs
0.0%
Results posted
Dec 2014
Primary outcomePrimary: Maximum Symptom Days/14 Days — 2.7 days
Summary
Asthma is a disease that affects more than 12% of Americans under the age of 18 for over 14 million missed school days per year, and is the number one cause of school absences in America. Elementary school children spend 6 to 10 hours a day in school, and most of that time is spent in one classroom. The goals of this project are to provide an understanding of exposure risk factors specific to the classroom. This is critical, because the classroom environment could potentially be considered as an effective target for prevention of inner-city asthma morbidity by reducing exposures to many symptomatic children through an intervention in the school classrooms.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Maximum Symptom Days/14 Days |
2.7 | — |
| SECONDARY Days of Slowed Activity Due to Asthma |
— | — |
| SECONDARY Days of Exercise-induced Symptoms |
— | — |
| SECONDARY Days of Cough Without an Upper Respiratory Infection |
— | — |
| SECONDARY Nights of Wakening Due to Asthma Symptoms |
— | — |
| SECONDARY Number of Hospitalizations |
— | — |
| SECONDARY Emergency Department Visits |
— | — |
| SECONDARY Unscheduled Physician/Health Care Visits |
— | — |
| SECONDARY Prednisone Bursts |
— | — |
| SECONDARY FEV1/FVC |
— | — |
| SECONDARY FEV1 Percent Predicted |
— | — |
| SECONDARY Percent Change in FEV1 After Short-acting Beta Agonist |
— | — |
| SECONDARY Exhaled Nitric Oxide Levels |
— | — |
Eligibility Criteria
Inclusion Criteria
- Grades K-8 the school year following spring recruitment (Ages 4-15)
- Attend one of the schools in the fall where permission obtained for classroom sampling.
- Able to provide assent and parent/guardian able to provide informed consent Physician-Diagnosed asthma AND Wheezing in the previous 12 months
Exclusion Criteria
- Significant pulmonary diseases other than asthma that might influence test results or pose risks (e.g., cystic fibrosis, sarcoidosis, bronchiectasis)
- Cardiovascular disease that requires daily medication
- Taking a beta blocker
- Active smoker
- Unable to follow through with study visit or complete study procedures
Data sourced from ClinicalTrials.gov (NCT01756391). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.