N/A
Completed N=50
Perioperative Aminophylline to Improve Early Kidney Function After a Kidney Transplant
Function of Renal Transplant
Source: ClinicalTrials.gov NCT01759862 ↗
Enrolled (actual)
50
Serious AEs
0.0%
Results posted
Mar 2019
Primary outcomePrimary: Calculated Estimated Glomerular Filtration Rate (eGFR) — 67.39; 80.48 ml/min/1.73m2 — p=0.32
Summary
The aim of this study is to evaluate whether peri-transplant administration of a drug named aminophylline to children undergoing a kidney transplant from deceased donors improves early graft function and also projects on long term graft function.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Calculated Estimated Glomerular Filtration Rate (eGFR) |
67.39; 80.48 | 0.32 |
| SECONDARY Urinary NGAL (Neutrophil Gelatinase-associated Lipocalin)/ Creatinine Ratio |
300.5; 425.4 | 0.95 |
Eligibility Criteria
Inclusion Criteria
- Pediatric kidney transplant recipients less than 21 years of age
- Patients undergoing deceased donor (DD) kidney transplants
Exclusion Criteria
- Known history of non-sinus tachycardia
- Multiple organ transplants recipients
- Severe liver dysfunction
- graft was placed on pump after harvesting
Data sourced from ClinicalTrials.gov (NCT01759862). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.