N/A N=74 Randomized Single-blind Prevention

Efficacy Study of a Novel Device to Clean the Endotracheal Tube

Endotracheal Extubation · Airway Obstruction · Airway Control · Pneumonia, Ventilator-Associated · Breathing Mechanics

Bottom Line

View on ClinicalTrials.gov: NCT01765530 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Mar 2017

Primary outcome: Primary: Percentage of Occlusion Assessed Using a High Definition Computed Tomography Imaging of the Extubated ETTs — 10.6; 17.7 percentage of occlusion

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: ETT cleaning maneuver (Device)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Massachusetts General Hospital
Primary completion: Dec 2013

Outcome Measures

Outcome	Result	p-value
PRIMARY Percentage of Occlusion Assessed Using a High Definition Computed Tomography Imaging of the Extubated ETTs	10.6; 17.7	—
SECONDARY ETT Microbiology	2.89; 3.35	—

Summary

The purpose of this study is to evaluate the in-vivo efficacy of a novel device (endOclear) for cleaning the endotracheal tube (ETT) lumen from secretions. The investigators hypothesize that a protocol of routine ETT cleaning with endOclear may increase the ETT luminal volume measured at extubation compared to the current standard of care. The device may therefore be clinically useful by better maintaining the ETT original function.

Eligibility Criteria

Inclusion Criteria

Age ≥ 18 years
Patients expected to be intubated for at least 48 hours or longer
Enrollment within 24 hours from intubation time

Exclusion Criteria

Current and past participation in another intervention trial conflicting with the present study
Pregnant women and prisoners

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01765530). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.