N/A
Completed N=74
Efficacy Study of a Novel Device to Clean the Endotracheal Tube
Endotracheal Extubation · Airway Obstruction · Airway Control · Pneumonia, Ventilator-Associated
Source: ClinicalTrials.gov NCT01765530 ↗
Enrolled (actual)
74
Serious AEs
0.0%
Results posted
Mar 2017
Primary outcomePrimary: Percentage of Occlusion Assessed Using a High Definition Computed Tomography Imaging of the Extubated ETTs — 10.6; 17.7 percentage of occlusion
Summary
The purpose of this study is to evaluate the in-vivo efficacy of a novel device (endOclear) for cleaning the endotracheal tube (ETT) lumen from secretions. The investigators hypothesize that a protocol of routine ETT cleaning with endOclear may increase the ETT luminal volume measured at extubation compared to the current standard of care. The device may therefore be clinically useful by better maintaining the ETT original function.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Percentage of Occlusion Assessed Using a High Definition Computed Tomography Imaging of the Extubated ETTs |
10.6; 17.7 | — |
| SECONDARY ETT Microbiology |
2.89; 3.35 | — |
Eligibility Criteria
Inclusion Criteria
- Age ≥ 18 years
- Patients expected to be intubated for at least 48 hours or longer
- Enrollment within 24 hours from intubation time
Exclusion Criteria
- Current and past participation in another intervention trial conflicting with the present study
- Pregnant women and prisoners
Data sourced from ClinicalTrials.gov (NCT01765530). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.