Phase 4
Completed N=50
The Effect of Platelet Rich Plasma (PRP) on Post Operative Pain in Anterior Cruciate Ligament Reconstruction
Post Operative Pain
Source: ClinicalTrials.gov NCT01765712 ↗
Enrolled (actual)
50
Serious AEs
0.0%
Results posted
Mar 2021
Primary outcomePrimary: Anterior Knee Pain — 2.4; 1.9 units on a scale — p=0.55
◆ Published Evidence
Established
59citations · ~7 / year
Effect of Intraoperative Platelet-Rich Plasma Treatment on Postoperative Donor Site Knee Pain in Patellar Tendon Autograft Anterior Cruciate Ligament Reconstruction: A Double-Blind Randomized Controlled Trial.
Summary
The purpose of this research study is to investigate whether or not platelet rich plasma (PRP) may help to improve tendon healing and decrease post operative pain in patients undergoing anterior cruciate ligament (ACL) reconstructive surgery using their own patellar tendons as autografts.
Linked Publications
-
Effect of Intraoperative Platelet-Rich Plasma Treatment on Postoperative Donor Site Knee Pain in Patellar Tendon Autograft Anterior Cruciate Ligament Reconstruction: A Double-Blind Randomized Controlled Trial.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Anterior Knee Pain |
2.4; 1.9 | 0.55 |
| SECONDARY Radiographic Assessment of Tunnel Positioning |
— | — |
| SECONDARY Quantification of Healing at the Bony and Tendinous Harvest Sites |
11.6; 12.0 | — |
| SECONDARY Post Operative Strength |
— | — |
| SECONDARY Post Operative Range of Motion |
— | — |
Eligibility Criteria
Inclusion Criteria
- Primary ACL Reconstruction
- Outerbridge </= 2
- Minimum follow up of two years
- No ligamentous secondary injury
- Willingness to participate in study
Exclusion Criteria
- Any previous knee injury
- prior history of anterior knee pain
- Outerbridge classification 3 or greater
- Revision ACL
- Diabetic or smoker
- Workers compensation patient
- pregnant or nursing women
- Any patient with limited English Proficiency
Data sourced from ClinicalTrials.gov (NCT01765712) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.