Phase 4
N=50
The Effect of Platelet Rich Plasma (PRP) on Post Operative Pain in Anterior Cruciate Ligament Reconstruction
Post Operative Pain
Bottom Line
View on ClinicalTrials.gov: NCT01765712 ↗Enrolled (actual)
50
Serious AEs
0.0%
Results posted
Mar 2021
Primary outcome: Primary: Anterior Knee Pain — 2.4; 1.9 units on a scale — p=0.55
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 4
- Interventions
- Anterior Cruciate ligament reconstruction bone patellar tendon bone autograft (Procedure); Platelet Rich Plasma (Biological)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Brian Walters
- Primary completion
- Aug 2017
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Anterior Knee Pain |
2.4; 1.9 | 0.55 |
| SECONDARY Radiographic Assessment of Tunnel Positioning |
— | — |
| SECONDARY Quantification of Healing at the Bony and Tendinous Harvest Sites |
11.6; 12.0 | — |
| SECONDARY Post Operative Strength |
— | — |
| SECONDARY Post Operative Range of Motion |
— | — |
Summary
The purpose of this research study is to investigate whether or not platelet rich plasma (PRP) may help to improve tendon healing and decrease post operative pain in patients undergoing anterior cruciate ligament (ACL) reconstructive surgery using their own patellar tendons as autografts.
Eligibility Criteria
Inclusion Criteria
- Primary ACL Reconstruction
- Outerbridge </= 2
- Minimum follow up of two years
- No ligamentous secondary injury
- Willingness to participate in study
Exclusion Criteria
- Any previous knee injury
- prior history of anterior knee pain
- Outerbridge classification 3 or greater
- Revision ACL
- Diabetic or smoker
- Workers compensation patient
- pregnant or nursing women
- Any patient with limited English Proficiency
Data sourced from ClinicalTrials.gov (NCT01765712). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.