The Effect of the Cosmetic Cream NMBM on Leg Ulcers - a Pilot Study

Inclusion Criteria

• Signed and dated written Institutional Review Board (IRB) or Independent Ethics Committee (IEC) approved informed consent obtained from the subject in accordance with the local regulations;
• Male or female subjects, ≥18 to ≤90 years of age
• Patient with venous or predominantly venous leg ulcer (ankle-brachial index > 0.8)
• Chronic venous insufficiency or post-erysipelas ulcer
• Ulcer size between 5 and 170 sq cm, inclusive
• Ulcer present for at least one month
• ankle-brachial index >0.7

Exclusion Criteria

• Suffers from diabetes mellitus with HbA1c ≥ 8%
• Albumin less than
• 2. Patients with the following abnormal laboratory test levels hemoglobin <10.5 g/dL platelet count <100 x 109/L serum albumin level < 2.5 g/dL 3. Suffers from clinically significant arterial disease 34. Has a known allergy to any of the compounds that are part of this protocol 45. Has evidence of the ulcer and / or infection extending to the underlying muscle, tendon or bone 56. Has used any investigational drug(s) within 30 days preceding randomization 67. Is unable to manage self-treatment 78. Is pregnant, nursing mother or a woman of child bearing potential who is not using an adequate form of contraception (or abstinence) 8. 9. Suffers from a condition which in the opinion of the Investigator would compromise the safety of the subject and / or the quality of the data 9. 10. Unwilling or unable to comply with study requirements.