N/A N=262

Maternal Serum Level of ACTH as a Predictive Marker of Preterm Labor in Patients With Threatened Preterm Labor

Threatened Preterm Labor

Bottom Line

View on ClinicalTrials.gov: NCT01773135 ↗

Enrolled (actual)

262

Serious AEs

—

Results posted

Apr 2014

Primary outcome: Primary: Evaluate if ACTH Can be Used as a Predictive Marker for Preterm Labor — 23.4; 19.3 pg/ml — p=<0.001

Study Design & Population

Study type: Observational
Phase: N/A
Interventions: collection of blood sample and tocolysis adminstration (Other)
Age: Pediatric, Adult · 17+ yrs
Sex: Female
Sponsor: Ain Shams Maternity Hospital
Primary completion: Oct 2013

Outcome Measures

Outcome	Result	p-value
PRIMARY Evaluate if ACTH Can be Used as a Predictive Marker for Preterm Labor	23.4; 19.3	<0.001 sig

Summary

The aim of this study is use of ACTH as a predictive marker in patients of threatened preterm labor .

Eligibility Criteria

Inclusion Criteria

Singleton pregnancy.
Age between 17 - 35 years.
Gestational age between 28 and 36 weeks.
Diagnosis of threatened preterm labor is based on the American College of Obstetricians and Gynaecologists Guidelines (ACOG, 2003): Presence of uterine contractions (at least 4 in 20 minutes or 8 in 60 minutes), Cervical dilation > 1 and < 4 cm, and/or Cervical effacement ≥ 80%.

Exclusion Criteria

Preterm rupture of membranes.
Any uterine anomalies or cervical incompetence.
Chronic illness such as chronic hypertension or kidney disease.
Diabetes mellitus.
Abruptio placenta.
Preeclampsia and HELLP syndrome.
Fetal anomalies.
IUGR.
Smoking.
Clinical signs of intrauterine infection eg (uterine tenderness, foul vaginal discharge, maternal pyrexia ≥ 38°C and/or maternal leucocytosis).

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Data sourced from ClinicalTrials.gov (NCT01773135). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.