Phase 4 Completed N=23 Randomized Double-blind Treatment

Insulin Sensitivity and Beta Cell Function After Carbohydrate Loading in Hip Replacement Surgery

Insulin Sensitivity

Source: ClinicalTrials.gov NCT01774084 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jun 2014

Primary outcomePrimary: Change in Insulin Sensitivity — 3.2; 2.4 mg/(kg min)

Summary

The purpose of this study is to determine whether preload of carbohydrate or water before elective hip replacement improve insulin sensitivity and or beta cell function in human.

Outcome Measures

Outcome	Result	p-value
PRIMARY Change in Insulin Sensitivity	3.2; 2.4	—
SECONDARY Change in Beta Cell Function	3.3; 2.6	—

Eligibility Criteria

Inclusion Criteria

Elective hip replacement

Exclusion Criteria

Known diabetes mellitus
Kidney failure (creatinine clearance <40 ml/min
Liver failure (aspartate and alanine aminotransferases x 2 above reference)
Hb <110 g/l
Ongoing severe bacterial or viral infection
Malignancies
Psychiatric disease

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01774084). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.