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N/A Completed N=2,259 Randomized Quadruple-blind Treatment

Whey Permeate Study

Source: ClinicalTrials.gov NCT01790048 ↗
Enrolled (actual)
2,259
Serious AEs
0.0%
Results posted
Jan 2019
Primary outcomePrimary: Recovery From Moderate Acute Malnutrition (MAM) — 960; 874 Participants

Summary

This is a prospective, randomized, double-blinded, controlled clinical effectiveness trial of two supplementary foods in the treatment of MAM. Specific Aim 1: Test the effectiveness of two supplementary foods, whey RUSF and soy RUSF, in the treatment of MAM in 6-59 month old children in a 12-week home-based supplementary feeding program. Hypothesis: The proportion of children who recover receiving either soy or whey RUSF will differ by no more than three percent.

Outcome Measures

OutcomeResultp-value
PRIMARY
Recovery From Moderate Acute Malnutrition (MAM)
960; 874
SECONDARY
Weight
2.95; 2.79
SECONDARY
Height
0.30; 0.29
SECONDARY
Mid-Upper-Arm Circumference (MUAC) Gain
0.26; 0.22
SECONDARY
Time to Graduation
29.3; 30.4
SECONDARY
Adverse Events
0; 0

Eligibility Criteria

Inclusion Criteria

  • Children with MAM defined as mid-upper-arm circumference, MUAC, ≤ 12.5 cm and > 11.5 cm without bipedal edema.

Exclusion Criteria

  • Children simultaneously involved in another research trial or supplemental feeding program
  • Children with developmentally delayed
  • Children with a chronic debilitating illness such as cerebral palsy (not including HIV or TB)
  • Children with a history of peanut or milk allergy
  • Children will also be excluded if they had received therapy for acute malnutrition within one month prior to presentation.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01790048). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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