N/A N=28 Randomized Single-blind Basic Science

Does Cold Provocation Increase Brown Adipose Tissue Volume?

Brown Adipose Tissue, Human

Bottom Line

View on ClinicalTrials.gov: NCT01797328 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Apr 2017

Primary outcome: Primary: Brown Adipose Tissue, Absolute Volume — 0.0066; 0.0021 liters

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: cold arm (Procedure); warm arm (Procedure)
Age: Adult · 18+ yrs
Sex: All
Sponsor: University Hospital, Linkoeping
Primary completion: May 2015

Outcome Measures

Outcome	Result	p-value
PRIMARY Brown Adipose Tissue, Absolute Volume	0.0066; 0.0021	—

Summary

About 28 healthy subjects are randomized to 1 hour/day of coldprovocation or to the best of ability to avoid feeling cold, for 6 weeks. Basal metabolic rate and magnetic resonance (for determination of brown adipose tissue volume) imaging are performed before and after the study.

Eligibility Criteria

Inclusion Criteria: healthy subjects - Exclusion Criteria: any significant disease, ot other conditions that interferes with magnetic resonance imaging -

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Data sourced from ClinicalTrials.gov (NCT01797328). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.