N/A
N=200
Impairment of Reading Ability in Dry Eye Patients
Dry Eye Syndromes
Bottom Line
View on ClinicalTrials.gov: NCT01826812 ↗Enrolled (actual)
200
Serious AEs
0.0%
Results posted
Mar 2016
Primary outcome: Primary: Sustained Silent Reading Speed — 248.4; 270.3 words/minute
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- 30 minutes sustained reading (Other); Dry eye exam (Other)
- Age
- Adult, Older Adult · 50+ yrs
- Sex
- All
- Sponsor
- Johns Hopkins University
- Primary completion
- Nov 2015
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Sustained Silent Reading Speed |
248.4; 270.3 | — |
| SECONDARY Change in Total Ocular Staining Score (OSS) |
1.5; 1.1 | — |
| SECONDARY Change in Tear Osmolarity |
2.7; 1.8 | — |
| SECONDARY Change in Visual Acuity |
0.02; 0.02 | — |
| SECONDARY Cytokines |
99.79; 150.10; 131.16; 107.53; 130.78; 69.64 | — |
Summary
To assess the reading function impairment in patients with dry eye and to assess the effects of reading on the ocular surface.
Eligibility Criteria
Inclusion Criteria
- age of 50 or greater,
- literacy in English language,
- ability to give informed consent
Exclusion Criteria
- binocular vision below 20/25,
- any ocular surgery within the last 3 months,
- mental issues,
- illiteracy,
- language problems which might possibly interfere with reading ability,
- history of taking or current use of topical prescription anti-inflammatory eye drops (including, cyclosporine and steroids as well as any glaucoma eye drops).
Data sourced from ClinicalTrials.gov (NCT01826812). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.