N/A
Completed N=200
Impairment of Reading Ability in Dry Eye Patients
Dry Eye Syndromes
Source: ClinicalTrials.gov NCT01826812 ↗
Enrolled (actual)
200
Serious AEs
0.0%
Results posted
Mar 2016
Primary outcomePrimary: Sustained Silent Reading Speed — 248.4; 270.3 words/minute
Summary
To assess the reading function impairment in patients with dry eye and to assess the effects of reading on the ocular surface.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Sustained Silent Reading Speed |
248.4; 270.3 | — |
| SECONDARY Change in Total Ocular Staining Score (OSS) |
1.5; 1.1 | — |
| SECONDARY Change in Tear Osmolarity |
2.7; 1.8 | — |
| SECONDARY Change in Visual Acuity |
0.02; 0.02 | — |
| SECONDARY Cytokines |
99.79; 150.10; 131.16; 107.53; 130.78; 69.64 | — |
Eligibility Criteria
Inclusion Criteria
- age of 50 or greater,
- literacy in English language,
- ability to give informed consent
Exclusion Criteria
- binocular vision below 20/25,
- any ocular surgery within the last 3 months,
- mental issues,
- illiteracy,
- language problems which might possibly interfere with reading ability,
- history of taking or current use of topical prescription anti-inflammatory eye drops (including, cyclosporine and steroids as well as any glaucoma eye drops).
Data sourced from ClinicalTrials.gov (NCT01826812). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.