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N/A N=49 Randomized Quadruple-blind Treatment

The Effect of Ultrasound on Orthodontic Tooth Movement

Malocclusion

Enrolled (actual)
49
Serious AEs
0.0%
Results posted
Apr 2017
Primary outcome: Primary: Rate of Tooth Movement — 0.266; 0.232 mm/week — p=0.0164

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Ultrasound (Device); Sham comparator (Device)
Age
Pediatric, Adult · 12+ yrs
Sex
All
Sponsor
SmileSonica Inc.
Primary completion
Jul 2015

Outcome Measures

OutcomeResultp-value
PRIMARY
Rate of Tooth Movement
0.266; 0.232 0.0164 sig
SECONDARY
Rate of Root Resorption
0.0092; 0.0241 0.0423 sig
SECONDARY
Discomfort
1.990; 2.000 <0.001 sig

Summary

To study whether or not the Aevo System™ medical device enhances the rate of tooth movement in human subjects who use orthodontic braces.

Eligibility Criteria

Inclusion Criteria

Subjects who meet all of the following criteria will qualify for entry into the study:

  • Scheduled to receive orthodontic treatment or in early stage of orthodontic treatment
  • Minimum of 3 mm of extraction space (on both sides of a dental arch) to be closed either by distal movement of all 6 anterior teeth from canine to canine or by distal movement of the canines.
  • Available for follow-up visits.
  • Willing and able to sign written informed consent.
  • Healthy.
  • Has permanent dentition and between the ages of 12 and 40.
  • Good oral hygiene and compliance

Exclusion Criteria

Subjects who meet any of the following criteria will be excluded from the study:

  • Any compromised medical or dental condition that prevents the subject from participating in the trial or using the medical device.
  • Any implanted assistive devices.
  • Currently involved in any other study.
  • Lives significantly outside the clinical trial site.
  • Use of bisphosphonates.
  • Pregnant females .
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01828164). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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