N/A
N=16
Exercise in Asymptomatic Pre-Alzheimer's Disease Pilot Study
Alzheimer's Disease Prevention
Bottom Line
View on ClinicalTrials.gov: NCT01834716 ↗Enrolled (actual)
16
Serious AEs
6.3%
Results posted
Mar 2019
Primary outcome: Primary: Number of Subjects Retained at 6 Months — 11; 4 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Aerobic vs. Non-Aerobic exercise (Behavioral)
- Age
- Older Adult · 65+ yrs
- Sex
- All
- Sponsor
- Mayo Clinic
- Primary completion
- Dec 2014
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Subjects Retained at 6 Months |
11; 4 | — |
Summary
Researchers are trying to determine if cognitively normal subjects undergoing a moderate aerobic exercise program will accumulate less amyloid-ß (Aβ) concentration in their brain than subjects undergoing a non-aerobic exercise program, and further evaluating the safety and imaging characteristics of florbetapir F 18, the radioactive drug that will allow us to image changes in the brain amyloid-ß (Aβ).
Eligibility Criteria
- 65 years of age or older.
- Not diagnosed with memory problems.
- Do not exercise in which you sweat and/or raise your pulse rate more than 30 minutes two times per week.
- Able to walk ten blocks (about one mile).
- Willing to participate in weekly exercise classes at the Brooks YMCA for six months.
- Able to have an MRI and CT/PET scan.
Data sourced from ClinicalTrials.gov (NCT01834716). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.