N/A N=22 Randomized Single-blind Treatment

Bone Augmentation Techniques in Extraction Sockets

Tooth Loss

Bottom Line

View on ClinicalTrials.gov: NCT01836783 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jun 2024

Primary outcome: Primary: Changes in Hard Tissue Composition — 35.82; 31.76 mm

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Amnion Allograft (Other); Allograft (Other)
Age: Adult, Older Adult · 19+ yrs
Sex: All
Sponsor: University of Alabama at Birmingham
Primary completion: Jun 2021

Outcome Measures

Outcome	Result	p-value
PRIMARY Changes in Hard Tissue Composition	35.82; 31.76	—
SECONDARY Changes in Soft Tissue Healing	0.87; 1.78	—
SECONDARY Changes in Soft Tissue Healing	0.87; 1.78	—

Summary

The study will compare the density and strength of regenerated bone in extraction sockets after being grafted with two different materials: Bone Allograft and Bone Allograft with Amnion. The investigators hypothesize that sockets grafted with the Amnion graft will exhibit enhanced healing patterns and will accelerate the formation of regenerated bone in the grafted areas.

Eligibility Criteria

Inclusion Criteria

Be a registered University of Alabama at Birmingham (UAB) dental school patient
Existence of one or more non-adjacent teeth in the aesthetic zone that are scheduled for extraction
Healthy enough to undergo the proposed therapy
Demonstrated willingness to comply with study directions and time-line
Able to consent for themselves
Able to read and understand the informed consent form -

Exclusion Criteria

Pregnant or lactating at the time of enrollment
Previous Malignant neoplasm
Known hypersensitivity to bone grafting materials
Know hypersensitivity to titanium
Any medical of medication that in the opinion of the investigators may adversely affect bone healing
Any indication of an inability to make autonomous decisions -

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01836783). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.