Phase 2 Completed N=52 Randomized Quadruple-blind Treatment

The Effect of Ondansetron on Cardiac Output in Elective Cesarean Deliveries

Cardiac Output

Source: ClinicalTrials.gov NCT01841606 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

May 2018

Primary outcomePrimary: Change in Cardiac Output From Baseline to 20 Minutes Post-spinal — -2.05; -1.92 L/min

Summary

Ondansetron is a medication routinely given to mothers having cesarean deliveries to help prevent and treat nausea and vomiting. The investigators are studying the hemodynamic effects of prophylactic ondansetron on parturients undergoing elective cesarean deliveries under spinal anesthesia.

Outcome Measures

Outcome	Result	p-value
PRIMARY Change in Cardiac Output From Baseline to 20 Minutes Post-spinal	-2.05; -1.92	—

Eligibility Criteria

Inclusion Criteria

Elective CD under spinal anesthesia
Fluency in English

Exclusion Criteria

Contraindication to spinal anesthesiA
Allergy to ondansetron

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01841606). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.