N/A
Completed N=300
Impact of Adding a Limitation Section in Abstract of Systematic Review
Systematic Review
Source: ClinicalTrials.gov NCT01848782 ↗
Enrolled (actual)
300
Serious AEs
0.0%
Results posted
May 2024
Primary outcomePrimary: Confidence in the Results of the Systematic Review — 4.6; 4.4 score on a scale — p=0.5
Summary
Objective: The investigators aim to evaluate the impact of a adding a " limitations " section in systematic review's abstract on result's interpretation by readers Design: randomized controlled trial with two parallel arms. Participants will be invited to participate in an online survey.
Participants: Eligible participants are corresponding authors of clinical trials published between 2010 and 2012 and referenced in Medline.
Intervention: The investigators will evaluate the impact of the presence of a " limitations " section in abstract of systematic review with meta- analysis. The investigators selected abstracts of meta-analysis from a sample.
Selected abstract will be standardised and the treatment's name hidden. Two groups of abstract will be presented as follow: 1) abstract without " limitations " section 2) abstract with " limitations " section. The " limitations " section will be written by authors and will briefly describe the risk of bias of included studies.
Selected participant are invited by e-mail to answer the survey. After reading one abstract from his/her group of randomisation they are invited to answer 5 questions about their interpretation of the results.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Confidence in the Results of the Systematic Review |
4.6; 4.4 | 0.5 |
| SECONDARY Confidence With the Validity of the Conclusions |
4.1; 4.0 | 0.8 |
| SECONDARY Beneficial Effect of the Experimental Intervention |
4.4; 4.3 | 0.6 |
| SECONDARY Influence of Results on Clinical Practice |
3.8; 3.8 | 0.8 |
| SECONDARY The Rigor of the Systematic Review |
4.1; 4.4 | 0.2 |
Eligibility Criteria
Inclusion Criteria
- corresponding authors of clinical trail indexed in pubmed with email address available
Data sourced from ClinicalTrials.gov (NCT01848782). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.