N/A
Completed N=24
Anterior Cruciate Ligament Reconstruction and Plyometric Exercise
Anterior Cruciate Ligament Reconstruction
Source: ClinicalTrials.gov NCT01851655 ↗
Enrolled (actual)
24
Serious AEs
0.0%
Results posted
Sep 2014
Primary outcomePrimary: Change in International Knee Documentation Committee (IKDC) Subjective Form Score. — 15.5; 12.1 units on a scale
Summary
This is a single-center, randomized, double-blind (subject/evaluator)study. Enrolled patients had anterior cruciate ligament (ACL) reconstruction and met criteria for advanced rehabilitation. The study included 8 weeks of advanced rehabilitation consisting of low- or high-intensity plyometric exercise. The objective of the study was to determine the effect of plyometric exercise intensity on knee function and knee cartilage in patients with ACL reconstruction.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in International Knee Documentation Committee (IKDC) Subjective Form Score. |
15.5; 12.1 | — |
| PRIMARY Change in Urinary Concentrations of the C-terminal Crosslinking Telopeptide of Type II Collagen (CTX-II) |
-0.1; -0.1 | — |
| SECONDARY Change in Vertical Jump Height. |
5.0; 2.6 | — |
| SECONDARY Change in the Ratio of Urinary CTXII to Serum CPII Concentrations. |
0.02; -0.01 | — |
Eligibility Criteria
Inclusion Criteria
- time from injury to ACL reconstruction is no greater than 6 months,
- pre-injury activity level includes participation in high-demand activities, and
- meet the criteria for advanced rehabilitation including full active knee extension, active knee flexion within 5 degrees of the contralateral side, pain rating no greater or equal to 1/10 with activities of daily living, and involved side knee extensor strength at least 60% of the contralateral side.
Exclusion Criteria
- bilateral knee injury,
- prior knee ligament injury and/or surgery,
- concomitant other ligamentous injury > Grade I,
- meniscal repair performed in conjunction with ACL reconstruction,
- cartilage repair procedure performed in conjunction with ACL reconstruction,
- complications during surgery requiring protocol modification, and
- renal disease.
Data sourced from ClinicalTrials.gov (NCT01851655). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.