N/A
N=24
Anterior Cruciate Ligament Reconstruction and Plyometric Exercise
Anterior Cruciate Ligament Reconstruction
Bottom Line
View on ClinicalTrials.gov: NCT01851655 ↗Enrolled (actual)
24
Serious AEs
0.0%
Results posted
Sep 2014
Primary outcome: Primary: Change in International Knee Documentation Committee (IKDC) Subjective Form Score. — 15.5; 12.1 units on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Plyometric Exercise (Behavioral)
- Age
- Pediatric, Adult · 15+ yrs
- Sex
- All
- Sponsor
- University of Florida
- Primary completion
- Jun 2010
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in International Knee Documentation Committee (IKDC) Subjective Form Score. |
15.5; 12.1 | — |
| PRIMARY Change in Urinary Concentrations of the C-terminal Crosslinking Telopeptide of Type II Collagen (CTX-II) |
-0.1; -0.1 | — |
| SECONDARY Change in Vertical Jump Height. |
5.0; 2.6 | — |
| SECONDARY Change in the Ratio of Urinary CTXII to Serum CPII Concentrations. |
0.02; -0.01 | — |
Summary
This is a single-center, randomized, double-blind (subject/evaluator)study. Enrolled patients had anterior cruciate ligament (ACL) reconstruction and met criteria for advanced rehabilitation. The study included 8 weeks of advanced rehabilitation consisting of low- or high-intensity plyometric exercise. The objective of the study was to determine the effect of plyometric exercise intensity on knee function and knee cartilage in patients with ACL reconstruction.
Eligibility Criteria
Inclusion Criteria
- time from injury to ACL reconstruction is no greater than 6 months,
- pre-injury activity level includes participation in high-demand activities, and
- meet the criteria for advanced rehabilitation including full active knee extension, active knee flexion within 5 degrees of the contralateral side, pain rating no greater or equal to 1/10 with activities of daily living, and involved side knee extensor strength at least 60% of the contralateral side.
Exclusion Criteria
- bilateral knee injury,
- prior knee ligament injury and/or surgery,
- concomitant other ligamentous injury > Grade I,
- meniscal repair performed in conjunction with ACL reconstruction,
- cartilage repair procedure performed in conjunction with ACL reconstruction,
- complications during surgery requiring protocol modification, and
- renal disease.
Data sourced from ClinicalTrials.gov (NCT01851655). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.