N/A
Completed N=108
Behavioral Differences in Effortful Control
Healthy
Source: ClinicalTrials.gov NCT01852344 ↗
Enrolled (actual)
108
Serious AEs
0.0%
Results posted
Jan 2018
Primary outcomePrimary: Reaction Time on the Multi-Source Interference Task — 300; 330; 310; 280 milliseconds — p=0.159
Summary
Effortful control refers to the mental processes that help a person to regulate his or her own attention, thoughts, and emotions. This study will examine behavioral differences in healthy individuals when performing a task that induces fatigue.
The purpose of this study is to examine the effects of methylphenidate on the cognitive functions in healthy individuals when performing fatiguing cognitive tasks.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Reaction Time on the Multi-Source Interference Task |
300; 330; 310; 280 | 0.159 |
| SECONDARY Accuracy on the Multi-Source Interference Task. |
94.1; 94.3; 96.1; 96.6 | 0.236 |
| SECONDARY Reaction Time Variability on the Multi-Source Interference Task. |
270; 320; 270; 260 | 0.032 sig |
Eligibility Criteria
Inclusion Criteria
- Age range 18-35
Exclusion Criteria
- Pregnant or nursing (females)
- Any clinically significant medical condition
- Currently taking any medications (i.e., decongestants)
- Currently taking any psychoactive medications
- Alcohol or substance abuse (current or in the past 2 years)
- Liver or Kidney disease
- Any clinically significant personal or family history of cardiac problems
Data sourced from ClinicalTrials.gov (NCT01852344). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.