N/A Completed N=33 Randomized Single-blind Basic Science

Effects of Light on Melatonin and Contractions in Pregnant Women

Source: ClinicalTrials.gov NCT01863446 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Nov 2023

Primary outcomePrimary: Melatonin Area Under the Curve (AUC) — 42.1; 24.3; 38.5; 26.3 area under curve (h*pg/mL) — p=0.334

Summary

Specific Aim: Test the hypothesis that ocular light exposure will suppress melatonin secretion and reduce uterine contractions in women at late term pregnancies. Secondary aim. Test the hypothesis that ocular light exposure will reduce self-reported uterine contractions in women at late term pregnancies.

Outcome Measures

Outcome	Result	p-value
PRIMARY Melatonin Area Under the Curve (AUC)	42.1; 24.3; 38.5; 26.3	0.334
SECONDARY Uterine Contractions	16.8; 13.8; 14.5; 13.0	0.780

Eligibility Criteria

Inclusion Criteria

pregnant at 35-40 weeks
first pregnancy

Exclusion Criteria

pregnancy-related complications
twin or higher pregnancy
using medication that affects the sympathetic nervous system

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01863446). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.