N/A
N=33
Effects of Light on Melatonin and Contractions in Pregnant Women
Pregnancy
Bottom Line
View on ClinicalTrials.gov: NCT01863446 ↗Enrolled (actual)
33
Serious AEs
0.0%
Results posted
Nov 2023
Primary outcome: Primary: Melatonin Area Under the Curve (AUC) — 42.1; 24.3; 38.5; 26.3 area under curve (h*pg/mL) — p=0.334
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Lighting1 (Device); Lighting2 (Device)
- Age
- Adult · 18+ yrs
- Sex
- Female
- Sponsor
- Brigham and Women's Hospital
- Primary completion
- Jun 2021
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Melatonin Area Under the Curve (AUC) |
42.1; 24.3; 38.5; 26.3 | 0.334 |
| SECONDARY Uterine Contractions |
16.8; 13.8; 14.5; 13.0 | 0.780 |
Summary
Specific Aim: Test the hypothesis that ocular light exposure will suppress melatonin secretion and reduce uterine contractions in women at late term pregnancies.
Secondary aim. Test the hypothesis that ocular light exposure will reduce self-reported uterine contractions in women at late term pregnancies.
Eligibility Criteria
Inclusion Criteria
- pregnant at 35-40 weeks
- first pregnancy
Exclusion Criteria
- pregnancy-related complications
- twin or higher pregnancy
- using medication that affects the sympathetic nervous system
Data sourced from ClinicalTrials.gov (NCT01863446). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.