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N/A N=1,404 Randomized Prevention

Comparison of Surgical Skin Preps During Cesarean Deliveries

Surgical Site Infection Following Cesarean Delivery

Enrolled (actual)
1,404
Serious AEs
0.5%
Results posted
Jun 2017
Primary outcome: Primary: Cesarean Surgical Site Infection — 18; 21; 21; 15 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Iodine povidone (Drug); Chlorhexidine (Drug); Combination iodine and chlorhexidine (Drug)
Age
Adult · 18+ yrs
Sex
Female
Sponsor
Montefiore Medical Center
Primary completion
Jul 2014

Outcome Measures

OutcomeResultp-value
PRIMARY
Cesarean Surgical Site Infection
18; 21; 21; 15; 15; 16

Summary

In women that undergo non-emergency cesarean delivery, we are comparing the skin preparation solutions for best outcome of surgical site infection. The three different solutions are: Group 1: Iodine povidone based skin preparation solution. Group 2: Chlorhexidine based skin preparation solution or Group 3: Combination usage of iodine povidone and chlorhexidine based skin preparation solutions. Women are prospectively randomized to one of the three groups and followed until thier postpartum visit at 6-8 weeks following delivery.

Eligibility Criteria

Inclusion Criteria

  • Gestational age > 37 weeks 0/7 days
  • Non-emergency indication for cesarean

Exclusion Criteria

  • Urogenital tract infection within 2 weeks prior to surgery
  • Chronic oral or injectable steroid use (> 2 weeks)
  • Emergency cesarean delivery
  • Participation in another research study
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01870583). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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