N/A
N=32
Physical Training and Heart Rate Variability in COPD
Chronic Obstructive Pulmonary Disease (COPD)
Bottom Line
View on ClinicalTrials.gov: NCT01889563 ↗Enrolled (actual)
32
Serious AEs
0.0%
Results posted
Jan 2014
Primary outcome: Primary: The SD1 Index, a Nonlinear Index of Heart Rate Variability (HRV)That Represents the Parassimpatetic Activity. — 3.7; 2.8; 7.1; 2.5 miliseconds
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Physical Exercise Training Program Exercise (Other)
- Age
- Adult, Older Adult · 45+ yrs
- Sex
- All
- Sponsor
- Universidade Federal de Sao Carlos
- Primary completion
- May 2008
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY The SD1 Index, a Nonlinear Index of Heart Rate Variability (HRV)That Represents the Parassimpatetic Activity. |
3.7; 2.8; 7.1; 2.5; 13.6; 2.5 | — |
| SECONDARY Walking Distance on Six Minute Walking Test |
341; 327; 596; 430; 602; 424 | — |
Summary
To contrast the potential effects of physical exercise training program (PTP) of a 6 versus 12 weeks on cardiac autonomic modulation by linear and non-linear heart rate variability (HRV) indices and functional capacity in moderate-to-severe COPD patients.
Eligibility Criteria
Inclusion Criteria
- a diagnosis of COPD according to criteria set forth by the Global Initiative for Chronic Obstructive Lung Disease (19),
- compliance with medical management,
- no change in medical management and no decompensation episodes for at least one month prior to study initiation, and
- no participation in a regular physical exercise program for at least six months prior to study initiation.
Exclusion Criteria
- presence of orthopedic or neurological conditions that would preclude participation in a physical exercise program,
- a history of cardiac arrhythmias,
- a past history consistent with heart disease, diabetes mellitus, arterial hypertension and failure to comply with the research protocol.
Data sourced from ClinicalTrials.gov (NCT01889563). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.