N/A
Completed N=32
Physical Training and Heart Rate Variability in COPD
Source: ClinicalTrials.gov NCT01889563 ↗Enrolled (actual)
32
Serious AEs
0.0%
Results posted
Jan 2014
Primary outcomePrimary: The SD1 Index, a Nonlinear Index of Heart Rate Variability (HRV)That Represents the Parassimpatetic Activity. — 3.7; 2.8; 7.1; 2.5 miliseconds
Summary
To contrast the potential effects of physical exercise training program (PTP) of a 6 versus 12 weeks on cardiac autonomic modulation by linear and non-linear heart rate variability (HRV) indices and functional capacity in moderate-to-severe COPD patients.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY The SD1 Index, a Nonlinear Index of Heart Rate Variability (HRV)That Represents the Parassimpatetic Activity. |
3.7; 2.8; 7.1; 2.5; 13.6; 2.5 | — |
| SECONDARY Walking Distance on Six Minute Walking Test |
341; 327; 596; 430; 602; 424 | — |
Eligibility Criteria
Inclusion Criteria
- a diagnosis of COPD according to criteria set forth by the Global Initiative for Chronic Obstructive Lung Disease (19),
- compliance with medical management,
- no change in medical management and no decompensation episodes for at least one month prior to study initiation, and
- no participation in a regular physical exercise program for at least six months prior to study initiation.
Exclusion Criteria
- presence of orthopedic or neurological conditions that would preclude participation in a physical exercise program,
- a history of cardiac arrhythmias,
- a past history consistent with heart disease, diabetes mellitus, arterial hypertension and failure to comply with the research protocol.
Data sourced from ClinicalTrials.gov (NCT01889563). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.