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N/A N=482

Special Investigation Of Genotropin Long Follow-Up For Patients With A Small For Gestational Age "Scoped for Japanese"

Small for Gestational Age (SGA)

Enrolled (actual)
482
Serious AEs
6.6%
Results posted
Feb 2020
Primary outcome: Primary: Number of Participants With Adverse Drug Reaction (ADR) — 24; 4 Participants

Study Design & Population

Study type
Observational
Phase
N/A
Interventions
Somatropin (Drug)
Age
Pediatric, Adult · 2+ yrs
Sex
All
Sponsor
Pfizer
Primary completion
Feb 2017

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Participants With Adverse Drug Reaction (ADR)
24; 4
PRIMARY
Change in Height Velocity Standard Deviation (SD) Score for Chronological Age From Baseline At Year 1
4.1
PRIMARY
Change in Height Velocity Standard Deviation (SD) Score for Chronological Age From Baseline at Year 2
3.0
PRIMARY
Change in Height Velocity Standard Deviation (SD) Score for Chronological Age From Baseline at Year 3
2.5
PRIMARY
Change in Height Velocity Standard Deviation (SD) Score for Chronological Age From Baseline at Year 4
2.6
PRIMARY
Change in Height Velocity Standard Deviation (SD) Score for Chronological Age From Baseline at Year 5
2.3
PRIMARY
Change in Height Velocity Standard Deviation (SD) Score for Chronological Age From Baseline at Year 6
2.4
PRIMARY
Change in Height Velocity Standard Deviation (SD) Score for Chronological Age From Baseline at Year 7
2.4
PRIMARY
Change in Height Velocity Standard Deviation (SD) Score for Chronological Age From Baseline at Year 10
-1.6
PRIMARY
Change in Height Standard Deviation (SD) Score for Chronological Age From Baseline at Year 1
0.6
PRIMARY
Change in Height Standard Deviation (SD) Score for Chronological Age From Baseline at Year 2
0.9
PRIMARY
Change in Height Standard Deviation (SD) Score for Chronological Age From Baseline at Year 3
1.1
PRIMARY
Change in Height Standard Deviation (SD) Score for Chronological Age From Baseline at Year 4
1.3
PRIMARY
Change in Height Standard Deviation (SD) Score for Chronological Age From Baseline at Year 5
1.3
PRIMARY
Change in Height Standard Deviation (SD) Score for Chronological Age From Baseline at Year 6
1.4
PRIMARY
Change in Height Standard Deviation (SD) Score for Chronological Age From Baseline at Year 7
1.4
PRIMARY
Change in Height Standard Deviation (SD) Score for Chronological Age From Baseline at Year 9
2.1
PRIMARY
Change in Height Standard Deviation (SD) Score for Chronological Age From Baseline at Year 10
1.8
SECONDARY
Height Standard Deviation (SD) Score at Puberty and at Near Final Height in Participants Who Reached Near Final Height
-3.1; -2.8; -2.5
SECONDARY
Change in Height Standard Deviation (SD) Score at Puberty and at Near Final Height in Participants Who Reached Near Final Height From Baseline
0.3; 0.6

Summary

The objective of this surveillance is to collect Safety and Effectiveness information for Long term Use of Somatropin for Patients with a Small for Gestational Age (SGA).

Eligibility Criteria

Inclusion Criteria

  • A patient who was administered Somatropin (Genotropin).

Exclusion Criteria

  • N/A.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01897766). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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