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N/A N=130 Treatment

Removal of the Evolution® Esophageal Stent - Fully Covered

Esophageal Fistula · Esophageal Neoplasms · Esophageal Perforation · Esophageal Stenosis · Stents

Enrolled (actual)
130
Serious AEs
35.4%
Results posted
Feb 2022
Primary outcome: Primary: Number of Patients With Successful Removal of Study Stent — 57 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Evolution® Esophageal Stent - Fully Covered (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Cook Group Incorporated
Primary completion
Dec 2018

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Patients With Successful Removal of Study Stent
57
SECONDARY
Number of Patients With Benign Indications That Achieved Clinical Success
44

Summary

The CLARITY study is a clinical trial approved by US FDA to study the removal of the Evolution® Esophageal Stent-Fully Covered in malignant and benign indications.

Eligibility Criteria

Inclusion Criteria

  • Patient is diagnosed with benign or malignant stricture, fistula, perforation, or leak
  • Physician plans to remove the stent within the duration of study follow-up

Exclusion Criteria

  • Patient is < 18 years of age
  • Patient is unable or unwilling to provide written informed consent or comply with follow-up schedule
  • Patient is pregnant, lactating, or planning on being pregnant within the next 6 months
  • Patient is simultaneously participating in another investigational drug or device study
  • Patient that is contraindicated to upper GI endoscopy and/or any procedure to be performed in conjunction with esophageal stent placement
  • Patient has a known hypersensitivity or contraindication to study products that, in the opinion of the investigator, cannot be adequately pre-medicated
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01900691). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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