N/A
Completed N=10
Matrix on Fruit Constituent Bioavailability
Healthy Non-smoker
Source: ClinicalTrials.gov NCT01908634 ↗
Enrolled (actual)
10
Serious AEs
0.0%
Results posted
Feb 2021
Primary outcomePrimary: CMax in Polyphenol Anthocyanin Concentrations — 8.7; 22.1; 7.6; 11.3 nmol/L
Summary
Primary objective is to evaluate the influence of matrix on the bioavailability of key phytochemical constituents in fruits and their subsequent effect on chronic disease risk factors.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY CMax in Polyphenol Anthocyanin Concentrations |
8.7; 22.1; 7.6; 11.3 | — |
Eligibility Criteria
Inclusion Criteria
- Adult (18-78 years of age)
- Relatively healthy
- Non-smoker or past smoker with abstinence for at least 2 years
Exclusion Criteria
- Pregnant and/or breast feeding
- Smoker or past smoker with abstinence 2 servings per day.
- Fasting blood glucose ≥ 126 mg/dL. Subjects identified with elevated fasting blood glucose levels will be advised to contact their primary care physician for appropriate follow-up care.
- Taking over the counter antioxidant supplements or other supplements that may interfere with the study procedures or endpoints.
- Subjects with unusual dietary habits (e.g. pica).
- Actively losing weight or trying to lose weight (unstable body weight fluctuations of > 5 lbs in a 60 day period).
- Excessive exercisers or trained athletes.
- Subjects with documented atherosclerotic disease, inflammatory disease, diabetes mellitus, or other systemic diseases.
- Addicted to drugs and/or alcohol.
- Medically documented psychiatric or neurological disturbances.
- Severe obesity as defined by >39.9 BMI or under weight for height (BMI <18.5)
Data sourced from ClinicalTrials.gov (NCT01908634). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.