N/A
Completed N=300
Postoperative Vomiting in Children - Is Dextrose an Effective Prophylactic Anti-emetic?
Postoperative Vomiting
Source: ClinicalTrials.gov NCT01912807 ↗
Enrolled (actual)
300
Serious AEs
0.0%
Results posted
Oct 2021
Primary outcomePrimary: Number of Participants With Postoperative Vomiting Between 0 to 2 Hours — 11; 5 Participants
Summary
The aim of this study was to investigate the efficacy of intraoperative intravenous dextrose in preventing POV in pediatric population undergoing dental day surgery.
Post-operative vomiting (POV) in children is a frequent complication. Studies using intravenous (IV) fluids containing dextrose in the perioperative period have shown improvement of POV in adults. Similar studies have not been done in children.
Knowing that Intravenous (IV) fluids containing dextrose are safe and commonly used in the paediatric population, this intervention could potentially reduce the amount of rescue antiemetic medications and improve recovery in same-day surgery paediatric patients.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Participants With Postoperative Vomiting Between 0 to 2 Hours |
11; 5 | — |
| SECONDARY Number of Participants Receiving Rescue Antiemetic Medications |
15; 9 | — |
Eligibility Criteria
Inclusion Criteria
- 3 to 9 Years of age
- Male and Female
- ASA I and II
- Paediatric patients undergoing same-day dental procedures at the Prairieview Surgical Centre.
Exclusion Criteria
- Age 9
- Underlying pro-emetic disease
- Positive history of POV in the patient, parent or sibling
- Currently on antiemetic medications
- Parent refusal to sign consent
- History of juvenile diabetes
Data sourced from ClinicalTrials.gov (NCT01912807). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.