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N/A N=500 Randomized Prevention

The Performance of Two Oxygen Delivery Devices Used After General Anesthesia.

Hypoxemia

Enrolled (actual)
500
Serious AEs
0.0%
Results posted
Jan 2017
Primary outcome: Primary: Number of Participants With Hypoxemia in Both Groups — 0; 0 number of participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
oxygen mask (Device); oxygen cannula (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Mahidol University
Primary completion
Nov 2014

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Participants With Hypoxemia in Both Groups
0; 0
SECONDARY
The Causes of Hypoxemia
0; 0

Summary

After general anesthesia, there are the risks for airway obstruction, hypoventilation, atelectasis, ventilation-perfusion mismatch, hypercarbia and hypoxemia,so oxygen supplement in PACU seems necessary. This study aim is to compare the two methods of oxygen supplement which are 1.nasal cannula at O2 flow 4 L/min. 2.oxygen mask with O2 flow 5 L/min. The hypothesis in this study is the 2 methods can equally provide effective oxygen supplement to prevent anesthesia-related hypoxemia. Choosing nasal cannula would be reasonable because it is cheaper and more comfortable to patient.

Eligibility Criteria

Inclusion Criteria

  • General anesthesia
  • Age 18-70 years
  • American Society of Anesthesiology (ASA)physical status 1-3
  • Elective case

Exclusion Criteria

  • ASA physical status class 4 or more
  • Unstable pulmonary diseases
  • BMI > 35 kg/m2
  • oxygen saturation < 94% when breathing in room air
  • Respiratory muscle weakness eg.myasthenia gravis
  • Central nervous system abnormalities eg.drowsiness, hypoventilation
  • Patients who have been intubated or needed ventilatory support before operation
  • Plan to remain intubated after the operation
  • Intracranial, intrathoracic and upper abdomen surgery
  • Patients who nasogastric tube is inserted
  • Airway problems eg. sinusitis
  • Nasal cavity related surgery or nasal packing eg. endoscopic sinus surgery
  • Patient refusal
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01917526). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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