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N/A N=22 Randomized

Human Skin Test Model in Colostomists

Colostomy Stoma

Enrolled (actual)
22
Serious AEs
0.0%
Results posted
Mar 2014
Primary outcome: Primary: Peel Force — 2.6; 2.1; 4.4; 3.4 Newton

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Hydrocolloid strip (Other); Strata strip (Other)
Age
Adult, Older Adult · 45+ yrs
Sex
All
Sponsor
Coloplast A/S
Primary completion
May 2012

Outcome Measures

OutcomeResultp-value
PRIMARY
Peel Force
2.6; 2.1; 4.4; 3.4

Summary

The aim of the study is to investigate the correlation in peel force when peeling off a standard hydrocolloid adhesive strip and standard strata adhesive strip from peristomal skin compared to pre-stripped healthy abdominal skin in colostomists.

Eligibility Criteria

Inclusion Criteria

  • Have given written informed consent.
  • Be in the age of 45 to 75 years of age both extremes included.
  • Have had a colostomy for at least 1 year.
  • Has a colostomy with a diameter up to (≤) 40 mm.
  • Have mental capacity to understand the study guidelines and questionnaires.
  • Be assessed by the investigator as having a peristomal and abdominal skin condition justifying entry into the investigation.
  • Are colostomists currently using a 1-piece and 2-piece flat ostomy appliance.
  • Have a BMI between 20-30 kg/m2.
  • Are willing to comply with investigation procedures.

Exclusion Criteria

  • Currently suffering from peristomal skin problems (i.e. bleeding or broken skin).
  • Received radio- and/or chemotherapy within the last two months.
  • Currently using or have within the last 3 weeks used topical steroid products or other skin prep products.

on peristomal skin (injections and oral treatment are accepted).

  • Have dermatological problems.
  • Participating in other clinical studies or have previously participated in this test.
  • Be a daily user of a convex base-plate.
  • Are pregnant or breastfeeding.
  • Systemic elements that could affect skin histology (e.g. liver, kidney or immunological diseases).
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01918085). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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